Toxicology studies

Inhalation toxicology studies, IND enabling, GLP or non-GLP, rodents and second species, with API-sparing possibilities.

General toxicology

Acute inhalation toxicology
OECD 403 & 436

Subacute inhalation toxicity
28-day study, OECD 412

Subchronic inhalation toxicity
90-day study, OECD 413
90-day inhalation toxicity, OPPTS 870.3465

Safety pharmacology

Reprotoxicity

Equipment

  • Solid aerosol generators
  • Nebulizers
  • Nose-only and whole-body exposure
  • Atmosphere control and monitoring