Intratracheal in vivo

Lung-specific one-animal-at-a-time intratracheal aerosol testing bypassing the nasal airways. Aerosol concertation and animal’s breathing patterns monitored throughout.


  • Individual control of inhaled dose
  • Standard deviation of typically <10%
  • Absorption profile of test substance in the systemic blood stream
  • Small amount of substance and animals required
  • Report: Full report including plasma and lung PK-data, Cmax and t1/2, and substance retained in lung

Catheter connected to PreciseInhale® (left) and systemic blood circulation PK-data of inhaled Fluticasone (right)

Intratracheal in vivo

IRS Brochure – Inhalation Research Services
Intratracheal Exposure Module – Technical Specifications