Intratracheal in vivo

Lung-specific one-animal-at-a-time intratracheal aerosol testing bypassing the nasal airways. Aerosol concertation and animal’s breathing patterns monitored throughout.

Delivers

• Individual control of inhaled dose
• Standard deviation of typically <10%
• Absorption profile of test substance in the systemic blood stream
• Small amount of substance and animals required
• Report: Full report including plasma and lung PK-data, Cmax and t1/2, and substance retained in lung